Ethical practices as viewed on the three ethics approaches can drive leader and employee involvement in sustainability-related behaviors. This study sought to determine the ethical practices of employees and leaders of a state university in the province of Laguna Philippines as well as the institution’s sustainability. Descriptive research was conducted through a survey administered to sixty-six (66) faculty members. The study also investigated if there are differences in the ethical practices of the leaders and employees when grouped according to profile factors as well as looked into the relationship between ethical practices and organization sustainability. The study revealed that the leaders and employees highly put into action the ethical practices in relation to Kantian, Virtue, and Care Ethics. Moreover, the level of sustainability exercised by the institution in terms of its contribution to society and the environment is perceived to be highly practiced. Furthermore, it was concluded that there is no significant difference in the ethical practices of the leaders as perceived by the faculty members. A significant relationship between ethical practices and organizational sustainability was established. As such, continuous review of the ethical code of conduct and laying down of procedures in carrying out ethical issues are emphasized by the results.